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個人技術(shù)特長

綜合利用生物學(xué)，計算機科學(xué)和信息技術(shù)而揭示大量而復(fù)雜的生物數(shù)據(jù)所賦有的生物學(xué)奧秘，在生物進化分析上建立了一套自己的分析研究體系，居于世界領(lǐng)先水平，可針對性的開發(fā)相關(guān)軟件或程序。

可提供對轉(zhuǎn)錄組、蛋白組、代謝組數(shù)據(jù)的解讀篩選，幫助客戶更快聚焦目的基因，探索生物學(xué)奧秘。此外還提供常規(guī)的DNA分析，RNA分析，蛋白分析，進化分析和繪圖等輔助性分析。

語言能力
英語 （精通）， 漢語 （中級）， 德語 （基層）， 克羅地亞語 （母語）

成果榮譽展示

代表論文：

1. Chen J, Ni P, Li X, Han J, Jakovli?I, Zhang C, et al. Population size may shape the accumulation of functional mutations following domestication. BMC Evol Biol. 2018;18: 4. doi:10.1186/s12862-018-1120-6

2. Jiang H, Hu Y, Wei X, Xiao X, Jakovli?I, Liu X, et al. Chemotactic effect ofβ-defensin 1 on macrophages in Megalobrama amblycephala. Fish Shellfish Immunol. 2018;74. doi:10.1016/j.fsi.2017.12.016ondrial genome of parasitic nematode Camallanus cotti: extreme discontinuity in the rate of mitogenomic architecture evolution within the Chromadorea class. BMC Genomics. 2017;18: 840. doi:10.1186/s12864-017-4237-x

4. Prathomya P, Prisingkorn W, Jakovli?I, Deng F-YF-Y, Zhao Y-H, Wang W-MW-M. 1H NMR-based metabolomics approach reveals metabolic alterations in response to dietary imbalances in Megalobrama amblycephala. Metabolomics. 2017;13: 17. doi:10.1007/s11306-016-1158-7

5. Prisingkorn W, Prathomya P, Jakovli?I, Liu H, Zhao Y-HH, Wang W-MM. Transcriptomics, metabolomics and histology indicate that high-carbohydrate diet negatively affects the liver health of blunt snout bream (Megalobrama amblycephala). BMC Genomics. 2017;18: 856. doi:10.1186/s12864-017-4246-9

6. Zhang D, Zou H, Wu SG, Li M, Jakovli?I, Zhang J, et al. Sequencing of the complete mitochondrial genome of a fish-parasitic flatworm Paratetraonchoides inermis (Platyhelminthes: Monogenea): tRNA gene arrangement reshuffling and implications for phylogeny. Parasit Vectors. 2017;10: 462. doi:10.1186/s13071-017-2404-1

7. Zhang D, Zou H, Wu SG, Li M, Jakovli?I, Zhang J, et al. Sequencing, characterization and phylogenomics of the complete mitochondrial genome of Dactylogyrus lamellatus (Monogenea: Dactylogyridae). J Helminthol. 2017; 1–12. doi:10.1017/S0022149X17000578

8. Liu F-F, Li Y-P, Jakovli?I, Yuan X-Q. Tandem duplication of two tRNA genes in the mitochondrial genome of Tagiades vajuna (Lepidoptera: Hesperiidae). EJE. 2017;114: 407–415. doi:10.14411/eje.2017.052

9. Wang J-G, Zhang D, Jakovli?I, Wang W-MW-M, Gui J, Hwang D-F. Sequencing of the complete mitochondrial genomes of eight freshwater snail species exposes pervasive paraphyly within the Viviparidae family (Caenogastropoda). PLoS One. Public Library of Science (PLoS); 2017;12: e0181699. doi:10.1371/journal.pone.0181699

10. Hao YT, Wu SG, Xiong F, Tran NT, Jakovli?I, Zou H, et al. Succession and fermentation products of grass carp (Ctenopharyngodon idellus) hindgut microbiota in response to an extreme dietary shift. Front Microbiol. 2017;8. doi:10.3389/fmicb.2017.01585

11. Hao YT, Wu SG, Jakovli?I, Zou H, Li WX, Wang GT. Impacts of diet on hindgut microbiota and short-chain fatty acids in grass carp (Ctenopharyngodon idellus). Aquac Res. 2017;48: 5595–5605. doi:10.1111/are.13381

12. Wang T, Gao X, Jakovli?I, Liu H-ZH-Z. Life tables and elasticity analyses of Yangtze River fish species with implications for conservation and management. Rev Fish Biol Fish. 2017;27. doi:10.1007/s11160-016-9464-8

13. Tran NT, Jakovli?I, Wang W-M. The first report of diablo in Megalobrama amblycephala: characterization, phylogenetic analysis, functional annotation and expression. J Genet. 2017;96: 613–623. doi:10.1007/s12041-017-0816-5

14. Zhan F-B, Liu H, Lai R-F, Jakovli?I, Wang W-M. Expression and functional characterization of interferon regulatory factors (irf2, irf7 and irf9) in the blunt snout bream (Megalobrama amblycephala). Dev Comp Immunol. 2017;67. doi:10.1016/j.dci.2016.09.014

15. Jakovli?I, Liu H, Wang W-M. Identification, origin and evidence for retained functionality of two IκBαparalogs in Megalobrama amblycephala. Dev Comp Immunol. 2016;62: 89–96. doi:10.1016/j.dci.2016.05.002

16. Jakovli?I, Wang W-M. Expression of Hox paralog group 13 genes in adult and developing Megalobrama amblycephala. Gene Expr Patterns. 2016;21: 63–68. doi:10.1016/j.gep.2016.07.001

17. Wang T, Jakovli?I, Huang D, Wang J-G, Shen J-Z. Reproductive strategy of the invasive sharpbelly, Hemiculter leucisculus (Basilewsky 1855), in Erhai Lake, China. J Appl Ichthyol. 2016;32. doi:10.1111/jai.13001

18. Lai R, Liu H, Jakovli?I, Zhan F, Wei J, Yang P, et al. Molecular cloning and expression of toll-like receptor 4 (tlr4) in the blunt snout bream (Megalobrama amblycephala). Dev Comp Immunol. 2016;59: 63–76. doi:10.1016/j.dci.2016.01.009

19. Zhan F-B, Liu H, Lai R-F, Jakovli?I, Wang W-B, Wang W-M. Molecular identification and functional characterisation of the interferon regulatory factor 1 in the blunt snout bream (Megalobrama amblycephala). Fish Shellfish Immunol. 2016;54: 456–465. doi:10.1016/j.fsi.2016.05.002

20. Lai R-F, Jakovli?I, Liu H, Zhan F-B, Wei J, Wang W-M. Molecular characterization and immunological response analysis of toll-like receptors from the blunt snout bream (Megalobrama amblycephala). Dev Comp Immunol. 2017;67. doi:10.1016/j.dci.2016.09.005

21. Lai RF, Jakovli?I, Liu H, Wei J, Zhan FB, Yang PH, et al. Characterization and expression of Megalobrama amblycephala toll-like receptor 22 involved in the response to Aeromonas hydrophila. J Fish Biol. 2017;90: 803–818. doi:10.1111/jfb.13199

22. Jakovli?I, Piria M,?prem N, Tomljanovi?T, Matuli?D, Treer T. Distribution, abundance and condition of invasive Ponto-Caspian gobies Ponticola kessleri (Günther, 1861), Neogobius fluviatilis (Pallas, 1814), and Neogobius melanostomus (Pallas, 1814) in the Sava River basin, Croatia. J Appl Ichthyol. 2015;31: n/a-n/a. doi:10.1111/jai.12803

23. Piria M, Jak?i?G, Jakovli?I, Treer T. Dietary habits of invasive Ponto-Caspian gobies in the Croatian part of the Danube River basin and their potential impact on benthic fish communities. Sci Total Environ. 2015; doi:10.1016/j.scitotenv.2015.05.125

24. Wang T, Gao X, Wang J, Jakovli?I, Dan S-G, Liu H-Z. Life history traits and implications for conservation of rock carp Procypris rabaudi Tchang, an endemic fish in the upper Yangtze River, China. Fish Sci. 2015;81: 515–523. doi:10.1007/s12562-015-0872-9

25. Tran N, Liu H, Jakovli?I, Wang W-M. Blunt Snout Bream (Megalobrama amblycephala) MyD88 and TRAF6: Characterisation, Comparative Homology Modelling and Expression. Int J Mol Sci. 2015;16: 7077–7097. doi:10.3390/ijms16047077

26. Tran NT, Jakovli?I, Wang W-M. In silico characterisation, homology modelling and structure-based functional annotation of blunt snout bream (Megalobrama amblycephala) Hsp70 and Hsc70 proteins. J Anim Sci Technol. 2015;57: 44. doi:10.1186/s40781-015-0077-x